专业从事离子液体的合成、应用及其相关技术的研究工作----Lanzhou Greenchem ILs/青岛奥立科

题名

参考引用方式

Yuanhong Xu, Lanyun Fang, Erkang Wang. Electrophoresis 2009, 30, 365–371

研究机构

中科院长春应用化学研究所

所涉及离子液体

1-丁基-3-甲基咪唑十二烷基硫酸盐 [BMIm][C12H25SO4]

研究领域

胶束毛细管电泳(MEKC)；电化学发光(ECL)

论文摘要

Herein, one water-soluble functionalized ionic liquid, 1-butyl-3-methylimidazolium dodecyl sulfate ([BMIm][C12H25SO4]), was designed and its superiorities either used as supporting electrolytes or as additives for successful establishment of MEKC with electrochemiluminescence (ECL) detection (MEKC-ECL) method were investigated. Compared with the common supporting electrolytes such as phosphate solution, 1-butyl-3-methylimidazolium dodecyl sulfate solution used as running buffers led to greatly enhanced ECL intensities and column efficiencies for negative targets, a little increase for neutral-charge ones while maintained nearly unchanged for positive ones due to the electrostatic forces between the large cation BMIm and the solutes and the hydrophobic interactions resulting from the large anion C12H25SO4. Moreover, resolution efficiency between analytes was significantly improved. As the existence of ionic liquid moiety, BMIm, accelerated the electron transfer at the electrode surface, the poisoning effect of long chain C12H25SO4 on the electrode surface was eliminated and reproducible ECL intensities with relative standard derivation of 1.02% (n=6) were obtained. The proposed novel MEKC-ECL system was again validated by the baseline separated two similar amino acids of proline and hydroxyproline with lower detection limits of 0.5 and 0.8 μM (S/N=3), respectively.

关键词

Electrochemiluminescence / Functionalized / Ionic liquid / MEKC